A significant decrease in the serum levels of folate, red blood cell folate were found in OED compared to normal tobacco smokers ( p39 years Mean serum levels of vitamin B 12, folate, and red blood cells folate in normal non-smokers and smokers control subjects compared with OED are detailed in Table 2. Serum folate, red blood cell folate and vitamin B 12 among cases and control subjects A significant decrease in the serum levels of folate, red blood cell folate was found in OED compared to normal tobacco smokers ( p 70
The majority of OED were graded either mild (46.7%) or moderate (40.0%) lesions and most of patients with OED were current smokers of more than 20 cigarettes per day for more than 20 years compared with normal healthy control. Measurement of serum folate and vitamin B 12 were carried out using radioassay. Data were collected from 120 patients with OED and 120 healthy control Subjects matched for age and gender, selected from patients with oral diseases not caused by tobacco or alcohol or related to knowing haematinic deficiency. To evaluate the circulating level of vitamin B 12, serum folate, red blood cells folate and iron among OED patients. The aims of this study were: to evaluate the circulating levels of vitamin B 12, folate status and iron, in patients with OED and to compare these levels with the values obtained in normal control subjects with and without tobacco smoking and alcohol drinking. Deficiency of vitamin B 12 and folate is associated with causation of certain precancerous and cancerous lesions. Oral epithelial dysplasia (OED) is a histopathologic diagnosis associated with an increased risk of cancer.
0 kommentar(er)
